#1.rare Apr 2026

In Pathfinder 2e , a "Rare" tag indicates that players usually need GM permission to choose that specific ancestry or feature because it is uncommon in the game world. 3. Medical Science: Rare Diseases

According to the World Health Organization (WHO), a disease is rare if it affects fewer than 65 out of every 100,000 people . #1.rare

Approximately 80% of these cases are genetic in origin, and they often present early in childhood. In Pathfinder 2e , a "Rare" tag indicates