Colossal

: The company aims to produce mammoth-like Asian elephant embryos by 2026, with the first calves expected by 2028.

Colossal aims to restore ecological balance by reintroducing "keystone" species to their original habitats. By reviving these animals, they hope to slow climate change—for example, by having woolly mammoths restore the Arctic grasslands to prevent permafrost melt.

: In April 2025, Colossal announced the birth of the first "functional de-extincted" animals: three dire wolf pups named Romulus, Remus, and Khaleesi.

In October 2024, the company launched the Colossal Foundation , a non-profit dedicated to applying these technologies to today's endangered species. They are currently working on a vaccine for a deadly elephant virus (EEHV) and biobanking the "top 100" most imperiled species to ensure their genetic survival.

: Their spin-off, Form Bio , uses AI to manage the massive datasets required for genomic assembly. The Colossal Foundation

: Working with the Mauritian Wildlife Foundation, they plan to return a proxy of the dodo to Mauritius within five to seven years.

: Used to splice ancient DNA traits into modern genomes.

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